Article
Family-based association study of polymorphisms in the RUNX2 locus with hand bone length and hand BMD.
Annals of human genetics - 1 Jul 2008
Ermakov S, Malkin I, Keter M, Kobyliansky E, Livshits G
Abstract excerpt
Osteoporosis is characterized by reduced bone strength. Bone size and bone mineral density (BMD) are major bone strength determinants. Identification of genes affecting the variability of these traits should improve prognosis and management of osteoporosis. This research was aimed to test the hypothesis of association of radiographic hand bone length (BL) and BMD with polymorphisms in the RUNX2 locus. Four SNPs...
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