Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ecNOS gene polymorphism is associated with endothelium-dependent vasodilation in Type 2 diabetes.

American journal of physiology. Heart and circulatory physiology - 1 Aug 2002

Komatsu Miyoko, Kawagishi Takahiko, Emoto Masanori, Shoji Tetsuo, Yamada Atsuko, Sato Kyoko, Hosoi Masayuki, Nishizawa Yoshiki

Abstract excerpt

The association between endothelial constitutive nitric oxide synthase (ecNOS) gene polymorphism and vascular endothelial function has not been clarified. We investigated the impact of ecNOS gene polymorphism on endothelial function in 95 patients with Type 2 diabetes (ecNOS genotype: 4b/b, n = 62; 4b/a, n = 30; 4a/a, n = 3). Flow-mediated (endothelium dependent, FMD) and nitroglycerin-induced (endothelium...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brachial Artery
Share to Endothelium, Vascular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nitric Oxide Synthase

Share to Nitric Oxide Synthase Type III

Share to Regional Blood Flow

Share to Smoking

Share to Vasodilation

Share to Vasodilator Agents

Source

Identifiers

PMID: 12124201
DOI: 10.1152/ajpheart.00653.2001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ecNOS gene polymorphism is associated with endothelium-dependent vasodilation in Type 2 diabetes.PMID 12124201Read ↗

Association of the endothelial nitric oxide synthase (ecNOS) gene polymorphism with carotid atherosclerosis in type 2 diabetes.Semantic proximity Read ↗

Endothelial nitric oxide synthase gene intron 4 polymorphism in type 2 diabetes mellitus.Semantic proximity Read ↗

Apolipoprotein e4 allele and endothelium-dependent arterial dilation in Type 2 diabetes mellitus without angiopathy.Semantic proximity Read ↗

A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene.Semantic proximity Read ↗

Apo e4 allele is associated with endothelium-dependent arterial dilation in women with type 2 diabetes.Semantic proximity Read ↗

A T-786C polymorphism in 5'-flanking region of the endothelial nitric oxide synthase gene and endothelium-dependent arterial dilation in Type 2 diabetes.Semantic proximity Read ↗

Endothelial NO-synthase intron 4 polymorphism is associated with disturbed in vivo nitric oxide production in individuals prone to type 2 diabetes.Semantic proximity Read ↗

Endothelium function biomarkers and carotid intima-media thickness changes in relation to NOS3 (rs2070744) and GNB3 (rs5443) genes polymorphism in the essential arterial hypertensionSemantic proximity Read ↗

Coronary artery disease and endothelial nitric oxide synthase and angiotensin-converting enzyme gene polymorphisms.Semantic proximity Read ↗

Endothelial nitric oxide synthase T(-786)C polymorphism in children and adolescents with type 1 diabetes and impaired endothelium-dependent dilatation.Semantic proximity Read ↗

Endothelial nitric oxide synthase (ecNOS) 4 a/b gene polymorphism and carotid artery intima-media thickness in type-1 diabetic patients.Semantic proximity Read ↗

Endothelial nitric oxide synthase gene polymorphism in intron 4 affects the progression of renal failure in non-diabetic renal diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.