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Article

Craniosynostosis: from a clinical description to an understanding of bone formation of the skull.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Nov 1999

Lajeunie E, Catala M, Renier D

Abstract excerpt

The genetic studies of syndromic craniosynostoses lead to the characterisation of genes that regulate the correct development of the bones of the skull. From these studies, it appears that FGF/FGFR signalling has a crucial role in this problem. Numerous mutations affecting the genes coding for FGFR1, 2 or 3 are responsible for these syndromes. It is interesting to note that some identical mutations produced...

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Source

Identifiers

PMID: 10603009
DOI: 10.1007/s003810050457

Genes

FGFR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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