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Article

Common 5' beta-globin RFLP haplotypes harbour a surprising level of ancestral sequence mosaicism.

Human genetics - 1 Jul 2003

Webster Matthew T, Clegg John B, Harding Rosalind M

Abstract excerpt

Blocks of linkage disequilibrium (LD) in the human genome represent segments of ancestral chromosomes. To investigate the relationship between LD and genealogy, we analysed diversity associated with restriction fragment length polymorphism (RFLP) haplotypes of the 5' beta-globin gene complex. Genealogical analyses were based on sequence alleles that spanned a 12.2-kb interval, covering 3.1 kb around the psibeta...

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PMID: 12736816
DOI: 10.1007/s00439-003-0954-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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