Article
Connective tissue growth factor is expressed in bone marrow stromal cells and promotes interleukin-7-dependent B lymphopoiesis.
Haematologica - 1 Jul 2014
Cheung Laurence C, Strickland Deborah H, Howlett Meegan, Ford Jette, Charles Adrian K, Lyons Karen M, Brigstock David R, Goldschmeding Roel, Cole Catherine H, Alexander Warren S, Kees Ursula R
Abstract excerpt
Hematopoiesis occurs in a complex bone marrow microenvironment in which bone marrow stromal cells provide critical support to the process through direct cell contact and indirectly through the secretion of cytokines and growth factors. We report that connective tissue growth factor (Ctgf, also known as Ccn2) is highly expressed in murine bone marrow stromal cells. In contrast, connective tissue growth factor is...
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