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Article

Single-molecule detection of efflux pump machinery in Pseudomonas aeruginosa.

Biochemical and biophysical research communications - 23 May 2003

Nancy Xu Xiao-Hong, Brownlow William, Huang Shuang, Chen Jun

Abstract excerpt

Real-time single-molecule microscopy and spectroscopy were used to monitor single molecules moving in and out of live bacterial cells, Pseudomonas aeruginosa. Ethidium bromide (EtBr) was chosen as the fluorescence probe because it emitted a weak fluorescence in aqueous solution (outside of the cells) and became strongly fluorescent as it entered the cells and intercalated with DNA. Such changes in fluorescence...

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PMID: 12732199
DOI: 10.1016/s0006-291x(03)00692-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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