Article
A DNA-binding-independent pathway of repression by the Drosophila Runt protein.
Blood cells, molecules & diseases - 1 Jan 2000
Vander Zwan Christine J, Wheeler John C, Li Ling-Hui, Tracey William D, Gergen J Peter
Abstract excerpt
DNA-binding proteins are important for regulating gene expression during development. It is widely assumed that this regulation involves sequence-specific DNA binding by these transcription factors to cognate cis-regulatory sequences of their downstream target genes. However, studies in both the Drosophila and the mouse model systems have provided examples in which the DNA-binding activity of a transcription...
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