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Article

Chronic Helicobacter pylori infections induce gastric mutations in mice.

Gastroenterology - 1 May 2003

Touati Eliette, Michel Valérie, Thiberge Jean-Michel, Wuscher Nicole, Huerre Michel, Labigne Agnès

Abstract excerpt

BACKGROUND & AIMS: Helicobacter pylori is an important etiologic factor in the development of gastric cancer. The aim of this study was to analyze the role of H. pylori infections in the induction of mutagenic events in gastric epithelial cells. The effect of a high-salt diet as a genotoxic risk factor was also investigated. METHODS: Big Blue transgenic male mice (C57Bl/6) were inoculated with H. pylori (strain...

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PMID: 12730880
DOI: 10.1016/s0016-5085(03)00266-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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