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Article

Towards understanding human mitochondrial leucine aminoacylation identity.

Journal of molecular biology - 16 May 2003

Sohm Bénédicte, Frugier Magali, Brulé Hervé, Olszak Krzysztof, Przykorska Anna, Florentz Catherine

Abstract excerpt

Specific recognition of tRNAs by aminoacyl-tRNA synthetases is governed by sets of aminoacylation identity elements, well defined for numerous prokaryotic systems and eukaryotic cytosolic systems. Only restricted information is available for aminoacylation of human mitochondrial tRNAs, despite their particularities linked to the non-classical structures of the tRNAs and their involvement in a growing number of...

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PMID: 12729737
DOI: 10.1016/s0022-2836(03)00373-5

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