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Article

Epigenetics in carcinogenesis and cancer prevention.

Annals of the New York Academy of Sciences - 1 Mar 2003

Jones Peter A

Abstract excerpt

Carcinogenesis is a stepwise process of accumulation of genetic and epigenetic abnormalities that can lead to cellular dysfunction. It has become clear that epigenetic changes are equally important for this multistep process to produce its results. This article describes the different roles that epigenetic modulation may play during carcinogenesis and how an early detection and chemopreventive intervention...

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Identifiers

PMID: 12724226
DOI: 10.1111/j.1749-6632.2003.tb05976.x

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