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Article

Threonine 157 of influenza virus PA polymerase subunit modulates RNA replication in infectious viruses.

Journal of virology - 1 May 2003

Huarte Maite, Falcón Ana, Nakaya Yuri, Ortín Juan, García-Sastre Adolfo, Nieto Amelia

Abstract excerpt

Previous results have shown a correlation between the decrease in protease activity of several influenza A virus PA protein mutants and the capacity to replicate of the corresponding mutant ribonucleoproteins (RNPs) reconstituted in vivo. In this work we studied the phenotype of mutant viruses containing these mutations. Viruses with a T162A mutation, which showed a very moderate decrease both in protease and...

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Identifiers

PMID: 12719592
DOI: 10.1128/jvi.77.10.6007-6013.2003
PMCID: PMC154019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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