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Article

Accumulation of large non-circular forms of the chromosome in recombination-defective mutants of Escherichia coli.

BMC molecular biology - 28 Apr 2003

Handa Naofumi, Kobayashi Ichizo

Abstract excerpt

BACKGROUND: Double-strand breakage of chromosomal DNA is obviously a serious threat to cells because various activities of the chromosome depend on its integrity. However, recent experiments suggest that such breakage may occur frequently during "normal" growth in various organisms - from bacteria through vertebrates, possibly through arrest of a replication fork at some endogenous DNA damage. RESULTS: In order...

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Identifiers

PMID: 12718760
DOI: 10.1186/1471-2199-4-5
PMCID: PMC156651

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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