Article
Brain immune responses cognitive decline and dementia: relationship with phenotype expression and genetic background.
Mechanisms of ageing and development - 1 Apr 2003
Licastro Federico, Chiappelli Martina
Abstract excerpt
Alzheimer's disease (AD) is a progressive degenerative disease of the brain and the most frequent cause of dementia among elderly. The etiology of AD is still obscure, but genetic and environmental factors appear to play differential roles in the disease. Several evidence suggest that inflammation or altered immune responses may play an important role in this disease. The following topics will be discussed: (1)...
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