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Article

Pseudogenization of the MCP-2/CCL8 chemokine gene in European rabbit (genus Oryctolagus), but not in species of Cottontail rabbit (Sylvilagus) and Hare (Lepus).

BMC genetics - 15 Aug 2012

van der Loo Wessel, Afonso Sandra, de Matos Ana Lemos, Abrantes Joana, Esteves Pedro J

Abstract excerpt

BACKGROUND: Recent studies in human have highlighted the importance of the monocyte chemotactic proteins (MCP) in leukocyte trafficking and their effects in inflammatory processes, tumor progression, and HIV-1 infection. In European rabbit (Oryctolagus cuniculus) one of the prime MCP targets, the chemokine receptor CCR5 underwent a unique structural alteration. Until now, no homologue of MCP-2/CCL8a, MCP-3/CCL7...

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Source

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Identifiers

PMID: 22894773
DOI: 10.1186/1471-2156-13-72
PMCID: PMC3511233

Genes

CCL8
CCL13
CCL7
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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