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Article

Multiplex genotyping of the human beta2-adrenergic receptor gene using solid-phase capturable dideoxynucleotides and mass spectrometry.

Analytical biochemistry - 15 May 2003

Kim Sobin, Shi Shundi, Bonome Tomás, Ulz Michael E, Edwards John R, Fodstad Heidi, Russo James J, Ju Jingyue

Abstract excerpt

Previously, we established the feasibility of using solid phase capturable (SPC) dideoxynucleotides to generate single base extension (SBE) products which were detected by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for multiplex genotyping, an approach that we refer to as SPC-SBE. We report here the expanding of the SPC-SBE method as a single-tube assay to...

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PMID: 12711347
DOI: 10.1016/s0003-2697(03)00080-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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