Article
Behavioral comparisons in autistic individuals from multiplex and singleton families.
Journal of autism and developmental disorders - 1 Feb 2003
Cuccaro Michael L, Shao Yujun, Bass Meredyth P, Abramson Ruth K, Ravan Sarah A, Wright Harry H, Wolpert Chantelle M, Donnelly Shannon L, Pericak-Vance Margaret A
Abstract excerpt
Autistic disorder (AD) is a complex neurodevelopmental disorder. The role of genetics in AD etiology is well established, and it is postulated that anywhere from 2 to 10 genes could be involved. As part of a larger study to identify these genetic effects we have ascertained a series of AD families: Sporadic (SP, 1 known AD case per family and no known history of AD) and multiplex (MP, > or = 2 cases per family)....
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