Article
Symptom domains in autism and related conditions: evidence for familiality.
American journal of medical genetics - 8 Jan 2002
Silverman Jeremy M, Smith Christopher J, Schmeidler James, Hollander Eric, Lawlor Brian A, Fitzgerald Michael, Buxbaum Joseph D, Delaney Katherine, Galvin Patricia
Abstract excerpt
Heterogeneity in autism impairs efforts to localize and identify the genes underlying this disorder. As autism comprises severe but variable deficits and traits in three symptom domains (social interaction, communication, and repetitive behaviors) and shows variability in the presence and emergence of useful phrase speech, different genetic factors may be associated with each. The affected cases (n=457) in...
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