Article
Force impairment in calpain 3-deficient mice is not correlated with mechanical disruption.
Muscle & nerve - 1 May 2003
Fougerousse Françoise, Gonin Patrick, Durand Muriel, Richard Isabelle, Raymackers Jean-Marc
Abstract excerpt
Defects in human calpain 3 are responsible for limb-girdle muscular dystrophy type 2A, an autosomal-recessive disorder characterized mainly by late-onset proximal muscular atrophy. A corresponding murine model has previously been generated by gene targeting. In this report, muscular activity of c...
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