Article
Potential Role of ADRA2A Genetic Variants in the Etiology of ADHD Comorbid With Tic Disorders.
Journal of attention disorders - 1 Jan 2021
Xu Defeng, Liu Lu, Li Haimei, Sun Li, Yang Li, Qian Qiujin, Wang Yufeng
Abstract excerpt
Objective: To evaluate the role of the adrenergic receptor alpha-2A gene (ADRA2A) in the genetic etiology of ADHD comorbid with tic disorders (ADHD+TD). Method: Two single nucleotide polymorphisms (SNPs) of ADRA2A were genotyped and analyzed in 936 normal controls and 1,815 ADHD probands, including 1,249 trios. Approximately 16% of the ADHD probands also had a diagnosis of TD. Results: No significant association...
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