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Article

Catecholamine-related gene expression in blood correlates with tic severity in tourette syndrome.

Psychiatry research - 30 Dec 2012

Gunther Joan, Tian Yingfang, Stamova Boryana, Lit Lisa, Corbett Blythe, Ander Brad, Zhan Xinhua, Jickling Glen, Bos-Veneman Netty, Liu Da, Hoekstra Pieter, Sharp Frank

Abstract excerpt

Tourette syndrome (TS) is a heritable disorder characterized by tics that are decreased in some patients by treatment with alpha adrenergic agonists and dopamine receptor blockers. Thus, this study examines the relationship between catecholamine gene expression in blood and tic severity. TS diagnosis was confirmed using Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV criteria and tic severity...

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Source

Identifiers

PMID: 22648010
DOI: 10.1016/j.psychres.2012.04.034

Genes

BDNF
DRD2
HRH3
MAOB
SNAP25

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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