Article
Evidence for joint action of genes on diabetes status and CVD risk factors in American Indians: the strong heart family study.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Apr 2003
North K E, Williams J T, Welty T K, Best L G, Lee E T, Fabsitz R R, Howard B V, MacCluer J W
Abstract excerpt
OBJECTIVES: Previous research among American Indians of the strong heart family study (SHFS) has demonstrated significant heritabilities for CVD risk factors and implicated diabetes as an important predictor of several of the phenotypes. Moreover, we recently demonstrated that genetic effects on CVD risk factors differed in diabetic and nondiabetic individuals. In this paper, we investigated whether a significant...
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