Article
The role of context-dependent mutations in generating compositional and codon usage bias in grass chloroplast DNA.
Journal of molecular evolution - 1 May 2003
Morton Brian R
Abstract excerpt
The influence of local base composition on mutations in chloroplast DNA (cpDNA) is studied in detail and the resulting, empirically derived, mutation dynamics are used to analyze both base composition and codon usage bias. A 4 x 4 substitution matrix is generated for each of the 16 possible flanking base combinations (contexts) using 17,253 noncoding sites, 1309 of which are variable, from an alignment of three...
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