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Article

A Novel Fusion Gene, SYT-SSX4, in Synovial Sarcoma

2 Jun 1999

Abstract excerpt

Cloning of the translocation t(X;18) (p11.2;q11.2) from human synovial sarcoma revealed a fusion between the SYT gene, also known as SSXT, located on chromosome 18 and the SSX gene located on the X chromosome ( 1 ). Five variants of the SSX gene (SSX1, SSX2, SSX3, SSX4, and SSX5) have been identified ( 2 ) but, to date, only SSX1 and SSX2 have been shown to fuse with the SYT gene in the translocation t(X;18) in...

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PMID: 10359553
DOI: 10.1093/jnci/91.11.974

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A Novel Fusion Gene, SYT-SSX4, in Synovial SarcomaPMID 10359553Read ↗

A variant of the SYT-SSX2 fusion gene in a case of synovial sarcoma.Semantic proximity Read ↗

The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome.Semantic proximity Read ↗

<i>SYT–SSX</i> Gene Fusion as a Determinant of Morphology and Prognosis in Synovial SarcomaSemantic proximity Read ↗

Identification of a novel spliced variant of the SYT gene expressed in normal tissues and in synovial sarcoma.Semantic proximity Read ↗

Clinical impact of molecular and cytogenetic findings in synovial sarcomaSemantic proximity Read ↗

Fusions of the SYT and SSX genes in synovial sarcoma.Semantic proximity Read ↗

Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcomaSemantic proximity Read ↗

A novel fusion gene, <i>SS18L1/SSX1</i>, in synovial sarcomaSemantic proximity Read ↗

Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel‐associated box in human synovial sarcoma.Semantic proximity Read ↗

The clinical implication of SS18 -SSX fusion gene in synovial sarcomaSemantic proximity Read ↗

Molecular mechanisms underlying human synovial sarcoma developmentSemantic proximity Read ↗

A case of primary synovial sarcoma of the thorax with a variant SYT-SSX1 fusion transcript.Semantic proximity Read ↗

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