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Article

Strategies for Development of Universal Vaccines Against Meningococcal Serogroup B Disease

6 Nov 2007

Abstract excerpt

A vaccine inducing protection against most of the circulating variants of serogroup B meningococcal strains is not yet available. A number of plausible options are currently under investigation. A conjugate vaccine based on a modified capsular polysaccharide might well work, but has safety concerns from molecular mimicry between group B sialic acid and human tissue. Recently, however, the group B capsule has been...

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PMID: 17712231
DOI: 10.4161/hv.4513

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