Article
Enzyme linked immunosorbent assay (ELISA) for the detection of serum antibodies to the inner core lipopolysaccharide of Neisseria meningitidis group B.
Journal of immunological methods - 3 Apr 2000
Plested J S, Gidney M A, Coull P A, Griffiths H G, Herbert M A, Bird A G, Richards J C, Moxon E R
Abstract excerpt
We have developed a solid-phase ELISA to study the human immune response to inner core lipopolysaccharide (LPS) of Neisseria meningitidis (Nm) using structurally defined glycolipids from a genetically defined mutant (galE) of a serogroup B Nm strain. Previous studies had demonstrated that a galE (inner core) LPS epitope is conserved in approximately 70% Nm strains and was accessible to antibody in fully...
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