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Article

Integrin-specific signaling pathways controlling focal adhesion formation and cell migration.

The Journal of cell biology - 14 Apr 2003

Mostafavi-Pour Zohreh, Askari Janet A, Parkinson Scott J, Parker Peter J, Ng Tony T C, Humphries Martin J

Abstract excerpt

The fibronectin (FN)-binding integrins alpha4beta1 and alpha5beta1 confer different cell adhesive properties, particularly with respect to focal adhesion formation and migration. After analyses of alpha4+/alpha5+ A375-SM melanoma cell adhesion to fragments of FN that interact selectively with alpha4beta1 and alpha5beta1, we now report two differences in the signals transduced by each receptor that underpin their...

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Identifiers

PMID: 12695503
DOI: 10.1083/jcb.200210176
PMCID: PMC2172880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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