Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiply Attenuated, Self-Inactivating Lentiviral Vectors Efficiently Deliver and Express Genes for Extended Periods of Time in Adult Rat Cardiomyocytes In Vivo

12 May 2003

Abstract excerpt

BACKGROUND: Among retroviral vectors, lentiviral vectors are unique in that they transduce genes into both dividing and nondividing cells. However, their ability to provide sustained myocardial transgene expression has not been evaluated. METHODS AND RESULTS: Multiply attenuated, self-inactivating lentivectors based on human immunodeficiency virus-1 contained the enhanced green fluorescent protein (EGFP) gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Viral Infections and Immunology Research
Share to Virus-based gene therapy research
Share to Xenotransplantation and immune response

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12695294
DOI: 10.1161/01.cir.0000065598.46411.ef

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiply Attenuated, Self-Inactivating Lentiviral Vectors Efficiently Deliver and Express Genes for Extended Periods of Time in Adult Rat Cardiomyocytes In VivoPMID 12695294Read ↗

Cardiomyocyte-specific Gene Expression Following Recombinant Adeno-associated Viral Vector TransductionSemantic proximity Read ↗

Multigene lentiviral vectors based on differential splicing and translational control.Semantic proximity Read ↗

Recent advances in lentiviral vector development and applications.Semantic proximity Read ↗

The Inside Out of Lentiviral VectorsSemantic proximity Read ↗

Transgenic enrichment of cardiomyocytes from human embryonic stem cells.Semantic proximity Read ↗

Reengineering Inducible Cardiac-Specific Transgenesis With an Attenuated Myosin Heavy Chain PromoterSemantic proximity Read ↗

Development of a Self-Inactivating Lentivirus VectorSemantic proximity Read ↗

HIV-1 vectors: fulfillment of expectations, further advancements, and still a way to go.Semantic proximity Read ↗

Integration-deficient lentiviral vectors: a slow coming of age.Semantic proximity Read ↗

Cardiac-Specific Gene Expression Facilitated by an Enhanced Myosin Light Chain PromoterSemantic proximity Read ↗

A Packaging Cell Line for Lentivirus VectorsSemantic proximity Read ↗

Efficient lentiviral transduction of different human and mouse cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.