Article
The C807T/G873A polymorphism in the platelet glycoprotein Ia gene and the risk of acute coronary syndrome in the Italian population.
British journal of haematology - 1 Jul 2001
Casorelli I, De Stefano V, Leone A M, Chiusolo P, Burzotta F, Paciaroni K, Rossi E, Andreotti F, Leone G, Maseri A
Abstract excerpt
Membrane glycoprotein (GP) Ia/IIa mediates platelet adhesion to collagen. The linked C807T/G873A polymorphisms in the GP Ia gene are correlated with a variable expression of the platelet surface receptor, the 807 TT/873 AA genotype being associated with a higher receptor density. Our study aimed to evaluate the possible role of the GP Ia C807T/G873A polymorphism as a risk factor for acute coronary syndrome in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
