Article
Heat shock protein 70 membrane expression and melanoma-associated marker phenotype in primary and metastatic melanoma.
Melanoma research - 1 Apr 2003
Farkas Beatrix, Hantschel Markus, Magyarlaki Marta, Becker Bernd, Scherer Kathrin, Landthaler Michael, Pfister Karin, Gehrmann Mathias, Gross Catharina, Mackensen Andreas, Multhoff Gabriele
Abstract excerpt
Cell membrane localization of the 72 kDa heat shock protein 70 (Hsp70) has been found on different tumour cell lines, on biopsy material from solid tumours and metastases and on leukaemic blasts from acute myelogenous leukaemia patients, but not on the corresponding normal tissues, as determined by flow cytometry using the Hsp70-specific monoclonal antibody C92F3B1. In the present study Hsp70 membrane expression...
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