Article
Hsp72-mediated augmentation of MHC class I surface expression and endogenous antigen presentation.
International immunology - 1 May 1998
Wells A D, Rai S K, Salvato M S, Band H, Malkovsky M
Abstract excerpt
Efficient recognition of tumor cells by cytolytic T lymphocytes (CTL) is often dependent on the presentation of cytosolic peptides in the context of MHC class I molecules. This process may be influenced by various molecular chaperones. To analyze this influence, we have utilized B16 melanoma cell...
Topics
- Animals
- Antigen Presentation
- Female
- Gene Expression
- HSP72 Heat-Shock Proteins
- Heat-Shock Proteins
- Histocompatibility Antigens Class I
- Humans
- Melanoma, Experimental
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
