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From Knowing to Controlling: A Path from Genomics to Drugs Using Small Molecule Probes

10 Apr 2003

Abstract excerpt

The National Cancer Institute Initiative in Chemical Genetics is designed to encourage the development of small molecular probes. The probes are useful for activating or inactivating protein functions, thereby providing resources that help discern the functions of gene products in normal and disease cells, as well as in tissues. This initiative includes "ChemBank," a suite of informatics tools and databases aimed...

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PMID: 12690189
DOI: 10.1126/science.1083395

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