Article
Rapid detection of resistance against rifampicin in isolates of Mycobacterium tuberculosis from Brazilian patients using a reverse-phase hybridization assay.
Journal of microbiological methods - 1 Jun 2003
de Oliveira Martha M, da Silva Rocha Adalgiza, Cardoso Oelemann Maraníbia, Gomes Harisson M, Fonseca Leila, Werneck-Barreto Angela M, Valim Andréia Moura, Rossetti Maria L, Rossau Rudi, Mijs Wouter, Vanderborght Bart, Suffys Philip
Abstract excerpt
The main objective of this study was to evaluate INNO-LiPA Rif.TB and to determine the frequency of mutations in rpoB in rifampicin-resistant Mycobacterium tuberculosis isolates of Brazilian tuberculosis patients. We used the reverse hybridization assay on 113 resistant and 15 sensitive clinical isolates of M. tuberculosis and on reference strains belonging to 37 different species. All MTB complex strains and...
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