Article
FGFR2 and WDR11 are neighboring oncogene and tumor suppressor gene on human chromosome 10q26.
International journal of oncology - 1 May 2003
Katoh Masuko, Katoh Masaru
Abstract excerpt
Oncogenes and tumor suppressor genes are clustered around recombination hot spots or fragile sites in the genome, because double-strand break is the common initial step in translocation, deletion and gene amplification. FGFR2 gene on human chromosome 10q26 is amplified in diffuse-type gastric can...
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