Article
INI-1, a partner gene of ALL-1, is highly conserved in human acute leukemia.
Oncology reports - 1 Jan 2000
Mimori Koshi, Inoue Hiroshi, Ishii Hideshi, Mori Masaki
Abstract excerpt
Recently, much interest have been focused on the role of INI-1, a partner gene of transfusion protein All-1 for leukemogenesis of acute leukemia cases. We found the presence of a mutation at codon 152 in INI-1 that resulted in a conservative amino acid change in cDNA and genomic DNA from an AML patient. We also found the known polymorphic nucleotide change at the third letter of codon 299 in exon 7 of INI-1 in 3...
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