Three model systems measure oxidation/nitration damage caused by peroxynitrite.

Abstract excerpt

Diseases activate the innate immune response which causes ancillary damage to the human body. Peroxynitrite (OONO-) or its carbon dioxide derivatives cause oxidation/nitration and hence mutation to various body polymers e.g. DNA, RNA, protein, lipids and sugars. The control of the ancillary damage can come from antioxidants which inhibit control the amount of peroxynitrite available for damage. In this paper we...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to DNA, Superhelical
• Share to Luciferases
• Share to Luminescent Measurements