Article
Spatial working memory as an endophenotype for schizophrenia.
Biological psychiatry - 1 Apr 2003
Glahn David C, Therman Sebastian, Manninen Marko, Huttunen Matti, Kaprio Joakko, Lönnqvist Jouko, Cannon Tyrone D
Abstract excerpt
BACKGROUND: Spatial working memory impairments are among the neurocognitive deficits that may mark genetic predisposition toward schizophrenia. We previously reported that impairment on the spatial span subtask of the Wechsler Adult Intelligence Scale-Revised increased in a dose-dependent manner with increasing genetic predisposition toward schizophrenia in a sample of discordant twins; however, it remains to be...
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