Article
Specification of neuropeptide cell identity by the integration of retrograde BMP signaling and a combinatorial transcription factor code.
Cell - 4 Apr 2003
Allan Douglas W, St Pierre Susan E, Miguel-Aliaga Irene, Thor Stefan
Abstract excerpt
Individual neurons express only one or a few of the many identified neurotransmitters and neuropeptides, but the molecular mechanisms controlling their selection are poorly understood. In the Drosophila ventral nerve cord, the six Tv neurons express the neuropeptide gene FMRFamide. Each Tv neuron resides within a neuronal cell group specified by the LIM-homeodomain gene apterous. We find that the zinc-finger gene...
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