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Article

Regulation of glial cell number and differentiation by ecdysone and Fos signaling.

Mechanisms of development - 1 Apr 2003

Giesen Kay, Lammel Uwe, Langehans Dirk, Krukkert Karin, Bunse Ingrid, Klämbt Christian

Abstract excerpt

In the midline glia of the embryonic ventral nerve cord of Drosophila, differentiation as well as the subsequent regulation of cell number is under the control of EGF-receptor signaling. During pupal stages apoptosis of all midline glial cells is initiated by ecdysone signaling. In a genetic screen we have identified mutations in disembodied, rippchen, spook, shade, shadow, shroud and tramtrack that all share a...

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Identifiers

PMID: 12676319
DOI: 10.1016/s0925-4773(03)00009-1

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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