Article
The alternative sigma factor RpoN regulates the quorum sensing gene rhlI in Pseudomonas aeruginosa.
FEMS microbiology letters - 28 Mar 2003
Thompson Lyndal S, Webb Jeremy S, Rice Scott A, Kjelleberg Staffan
Abstract excerpt
The rhl quorum sensing (QS) circuit of Pseudomonas aeruginosa is known to regulate the expression of a number of virulence factors. This study investigates the regulation of rhlI, encoding the auto-inducer synthase RhlI responsible for the synthesis of N-butryl-L-homoserine lactone (BHL). A putative RpoN binding site was located upstream, in the promoter region of rhlI. Utilising a rhlI-lacZ transcriptional...
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