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Article

Identification and characterization of Helicobacter pylori genes essential for gastric colonization.

The Journal of experimental medicine - 7 Apr 2003

Kavermann Holger, Burns Brendan P, Angermuller Katrin, Odenbreit Stefan, Fischer Wolfgang, Melchers Klaus, Haas Rainer

Abstract excerpt

Helicobacter pylori causes one of the most common, chronic bacterial infections and is a primary cause of severe gastric disorders. To unravel the bacterial factors necessary for the process of gastric colonization and pathogenesis, signature tagged mutagenesis (STM) was adapted to H. pylori. The Mongolian gerbil (Meriones unguiculatus) was used as model system to screen a set of 960 STM mutants. This resulted in...

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Identifiers

PMID: 12668646
DOI: 10.1084/jem.20021531
PMCID: PMC2193887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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