Article
Genetic alterations detected on chromosomes 13 and 14 in Chinese non-small cell lung carcinomas.
Cancer letters - 31 Mar 2003
Kwong Fung Mei, Wong Po Shan, Lung Maria Li
Abstract excerpt
Genetic alterations in 28 non-small cell lung carcinoma patients were detected on chromosomes 13q and 14q with microsatellite markers by polymerase chain reaction techniques. Loss of heterozygosity of up to 50% was detected with chromosome 13 markers and of up to 37% for chromosome 14. Microsatellite instability was as high as 30% on chromosome 13 and up to 19% on chromosome 14. Accumulated mutation frequencies...
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