Article
Expression of hMSH2 gene and mutant p53 in sporadic digestive tract tumors.
Chinese medical journal - 1 Jan 2003
Kang Yanjie, Zhang Zhenke, Wang Junxia, Chen Jing, Peng Bo, Kang Ping
Abstract excerpt
OBJECTIVE: To investigate the role of mutated mismatch repair gene hMSH2 and mutant p53 gene in the carcinogenesis and development of sporadic digestive tract tumors. METHODS: hMSH2 gene in normal and tumor tissue of 30 digestive tract tumor specimens was examined using polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) silver staining. The PCR product with an abnormal strand was...
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