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Article

Mapping quantitative trait loci in the case of a spike in the phenotype distribution.

Genetics - 1 Mar 2003

Broman Karl W

Abstract excerpt

A common departure from the usual normality assumption in QTL mapping concerns a spike in the phenotype distribution. For example, in measurements of tumor mass, some individuals may exhibit no tumors; in measurements of time to death after a bacterial infection, some individuals may recover from the infection and fail to die. If an appreciable portion of individuals share a common phenotype value (generally...

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Identifiers

PMID: 12663553
DOI: 10.1093/genetics/163.3.1169
PMCID: PMC1462498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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