Article
Identification of two keratinocyte stem cell regulatory loci implicated in skin carcinogenesis.
Carcinogenesis - 1 Mar 2003
Popova Natalia V, Teti Kimberly A, Wu Kai Q, Morris Rebecca J
Abstract excerpt
Several converging lines of evidence suggest that keratinocyte stem cells including those clonogenic in vitro, are the target cells in skin carcinogenesis. However, the mechanism of their involvement in carcinogenesis continues to be unknown. Recently, we have demonstrated that the number of keratinocyte clonogenic stem cells from mice is a genetically defined and quantitative complex trait. In this study, we...
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