Article
Genetic liability of type 1 diabetes and the onset age among 22,650 young Finnish twin pairs: a nationwide follow-up study.
Diabetes - 1 Apr 2003
Hyttinen Valma, Kaprio Jaakko, Kinnunen Leena, Koskenvuo Markku, Tuomilehto Jaakko
Abstract excerpt
Finland has the world's highest incidence of type 1 diabetes, and it is steadily increasing. We determined concordance rates and estimated heritability for type 1 diabetes in the Finnish Twin Cohort, a population-based twin cohort of 22,650 twin pairs. In addition, we studied age of onset in the first affected twin and discordance time between concordant twin pairs. Finnish twins born between 1958 and 1986 were...
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