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Article

Programming of islet functions in the progeny of hyperinsulinemic/obese rats.

Diabetes - 1 Apr 2003

Srinivasan Malathi, Aalinkeel Ravikumar, Song Fei, Patel Mulchand S

Abstract excerpt

Neonatal female rat pups that were raised artificially on a high-carbohydrate (HC) milk formula during their suckling period developed hyperinsulinemia immediately, maintained chronic hyperinsulinemia in the postweaning period on laboratory diet, and developed obesity in adulthood. Pups (second-generation HC [2-HC]) born to such female rats (first-generation HC [1-HC]) spontaneously developed chronic...

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Identifiers

PMID: 12663470
DOI: 10.2337/diabetes.52.4.984

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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