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Maternal Western-style diet affects offspring islet composition and function in a non-human primate model of maternal over-nutrition

12 Apr 2019

Abstract excerpt

OBJECTIVE: In humans, offspring of women who are overweight or obese are more likely to develop metabolic disease later in life. Studies in lower animal species reveal that a calorically-dense maternal diet is associated with alterations in islet cell mass and function. The long-term effects of maternal diet on the structure and function of offspring islets with characteristics similar to humans are unknown. We...

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PMID: 31036449
DOI: 10.1016/j.molmet.2019.03.010

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