Article
Group AStreptococcusGene Expression in Humans and Cynomolgus Macaques with Acute Pharyngitis
24 Mar 2003
Abstract excerpt
The molecular mechanisms used by group A Streptococcus (GAS) to survive on the host mucosal surface and cause acute pharyngitis are poorly understood. To provide new information about GAS host-pathogen interactions, we used real-time reverse transcription-PCR (RT-PCR) to analyze transcripts of 17 GAS genes in throat swab specimens taken from 18 pediatric patients with pharyngitis. The expression of known and...
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