Article
Colonization of C57BL/6J and BALB/c Wild-Type and Knockout Mice withHelicobacter pylori: Effect of Vaccination and Implications for Innate and Acquired Immunity
22 Jan 2003
Abstract excerpt
The gram-negative bacterial pathogen Helicobacter pylori is a major cause of peptic ulcer disease and a risk factor for gastric cancer in humans. Adapted H. pylori strains, such as strain SS1, are able to infect mice and are a useful model for gastric colonization and vaccination studies. In this study we used a streptomycin-resistant derivative of H. pylori SS1 to analyze the colonization behavior and the...
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