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Article

Characterization of human cardiac Na <sup>+</sup> channel mutations in the congenital long QT syndrome

12 Nov 1996

Abstract excerpt

The congenital long QT syndrome (LQTS) is an inherited disorder characterized by a prolonged cardiac action potential. This delay in cellular repolarization can lead to potentially fatal arrhythmias. One form of LQTS (LQT3) has been linked to the human cardiac voltage-gated sodium channel gene (SCN5A). Three distinct mutations have been identified in the sodium channel gene. The biophysical and functional...

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Identifiers

PMID: 8917568
DOI: 10.1073/pnas.93.23.13200

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of human cardiac Na <sup>+</sup> channel mutations in the congenital long QT syndromePMID 8917568Read ↗

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